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Catalytic Asymmetric Synthesis of Both Enantiomers of 4‑Substituted 1,4-Dihydropyridines with the Use of Bifunctional Thiourea-Ammonium Salts Bearing Different Counterions

Organoammonium salts composed of a Brønsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively. With the use of the different Brønsted acids such as...

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Main Authors: Kohzo Yoshida, Tsubasa Inokuma, Kiyosei Takasu, Yoshiji Takemoto
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI AG 2010-11-01
Sraith:Molecules
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Rochtain Ar Líne:http://www.mdpi.com/1420-3049/15/11/8305/
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