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A Catalytic, Asymmetric Formal Synthesis of (+)-Hamigeran B

[Image: see text] A concise asymmetric, formal synthesis of (+)-hamigeran B is reported. A Pd-catalyzed, decarboxylative allylic alkylation, employing a trifluoromethylated derivative of t-BuPHOX, is utilized as the enantioselective step to form the critical quaternary carbon center in excellent yie...

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Détails bibliographiques
Auteurs principaux: Mukherjee, Herschel, McDougal, Nolan T., Virgil, Scott C., Stoltz, Brian M.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045637/
https://ncbi.nlm.nih.gov/pubmed/21271716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol102669z
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