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High-Throughput Screening of the Asymmetric Decarboxylative Alkylation Reaction of Enolate-Stabilized Enol Carbonates

The use of high-throughput screening allowed for the optimization of reaction conditions for the palladium-catalyzed asymmetric decarboxylative alkylation reaction of enolate-stabilized enol carbonates. Changing to a non-polar reaction solvent and to an electron-deficient PHOX derivative as ligand f...

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Autori principali: McDougal, Nolan T., Virgil, Scott C., Stoltz, Brian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976558/
https://ncbi.nlm.nih.gov/pubmed/21072327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0030-1258094
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