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Synthesis of (-)-Hamigeran B

The synthesis of (-)-hamigeran B has been achieved, based on a new approach to cyclopentane construction, the rhodium-mediated intramolecular C-H insertion of α-aryl-α-diazo ketones. The endo isopropyl group was installed by selective hydrogenation of a cyclopropylidene substituent.

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Bibliografiske detaljer
Main Authors: Taber, Douglass F., Tian, Weiwei
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626181/
https://ncbi.nlm.nih.gov/pubmed/18771326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo8010683
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