NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis

The leukocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase generates reactive oxygen species essential in microbial killing and regulation of inflammation. Inactivating mutations in this enzyme lead to chronic granulomatous disease (CGD), associated with increased susceptibility to bo...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Bagaitkar, Juhi, Pech, Nancy K., Ivanov, Stoyan, Austin, Anthony, Zeng, Melody Yue, Pallat, Sabine, Huang, Guangming, Randolph, Gwendalyn J., Dinauer, Mary C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Phagocytes, Granulocytes, and Myelopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683333/
https://ncbi.nlm.nih.gov/pubmed/26443623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644773
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