NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis

The leukocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase generates reactive oxygen species essential in microbial killing and regulation of inflammation. Inactivating mutations in this enzyme lead to chronic granulomatous disease (CGD), associated with increased susceptibility to bo...

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Pubblicato in:Blood
Autori principali: Bagaitkar, Juhi, Pech, Nancy K., Ivanov, Stoyan, Austin, Anthony, Zeng, Melody Yue, Pallat, Sabine, Huang, Guangming, Randolph, Gwendalyn J., Dinauer, Mary C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
Soggetti:
Phagocytes, Granulocytes, and Myelopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683333/
https://ncbi.nlm.nih.gov/pubmed/26443623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644773
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