NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis

The leukocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase generates reactive oxygen species essential in microbial killing and regulation of inflammation. Inactivating mutations in this enzyme lead to chronic granulomatous disease (CGD), associated with increased susceptibility to bo...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Bagaitkar, Juhi, Pech, Nancy K., Ivanov, Stoyan, Austin, Anthony, Zeng, Melody Yue, Pallat, Sabine, Huang, Guangming, Randolph, Gwendalyn J., Dinauer, Mary C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Phagocytes, Granulocytes, and Myelopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683333/
https://ncbi.nlm.nih.gov/pubmed/26443623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644773
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