NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis

The leukocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase generates reactive oxygen species essential in microbial killing and regulation of inflammation. Inactivating mutations in this enzyme lead to chronic granulomatous disease (CGD), associated with increased susceptibility to bo...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Bagaitkar, Juhi, Pech, Nancy K., Ivanov, Stoyan, Austin, Anthony, Zeng, Melody Yue, Pallat, Sabine, Huang, Guangming, Randolph, Gwendalyn J., Dinauer, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683333/
https://ncbi.nlm.nih.gov/pubmed/26443623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644773
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