An efferocytosis-induced, IL-4–dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD

Efferocytosis of apoptotic neutrophils by macrophages following tissue injury is fundamental to the resolution of inflammation and initiation of tissue repair. Using a sterile peritonitis model in mice, we identified interleukin (IL)-4–producing efferocytosing macrophages in the peritoneum that acti...

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Bibliografiske detaljer
Main Authors: Zeng, Melody Yue, Pham, Duy, Bagaitkar, Juhi, Liu, Jianyun, Otero, Karel, Shan, Ming, Wynn, Thomas A., Brombacher, Frank, Brutkiewicz, Randy R., Kaplan, Mark H., Dinauer, Mary C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Phagocytes, Granulocytes, and Myelopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637016/
https://ncbi.nlm.nih.gov/pubmed/23426944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-461913
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