NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages

The phagocyte reduced NAD phosphate (NADPH) oxidase generates superoxide, the precursor to reactive oxygen species (ROS) that has both antimicrobial and immunoregulatory functions. Inactivating mutations in NADPH oxidase alleles cause chronic granulomatous disease (CGD), characterized by enhanced su...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Bagaitkar, Juhi, Huang, Jing, Zeng, Melody Yue, Pech, Nancy K., Monlish, Darlene A., Perez-Zapata, Lizet J., Miralda, Irina, Schuettpelz, Laura G., Dinauer, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969376/
https://ncbi.nlm.nih.gov/pubmed/29618478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-09-809004
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