NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages

The phagocyte reduced NAD phosphate (NADPH) oxidase generates superoxide, the precursor to reactive oxygen species (ROS) that has both antimicrobial and immunoregulatory functions. Inactivating mutations in NADPH oxidase alleles cause chronic granulomatous disease (CGD), characterized by enhanced su...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Bagaitkar, Juhi, Huang, Jing, Zeng, Melody Yue, Pech, Nancy K., Monlish, Darlene A., Perez-Zapata, Lizet J., Miralda, Irina, Schuettpelz, Laura G., Dinauer, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2018
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969376/
https://ncbi.nlm.nih.gov/pubmed/29618478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-09-809004
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