NADPH oxidase correction by mRNA transfection of apheresis granulocytes in chronic granulomatous disease

Granulocytes from patients with chronic granulomatous disease (CGD) have dysfunctional phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase that fails to generate sufficient antimicrobial reactive oxidative species. CGD patients with severe persistent fungal or bacterial inf...

詳細記述

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書誌詳細
出版年:Blood Adv
主要な著者: De Ravin, Suk See, Brault, Julie, Meis, Ronald J., Li, Linhong, Theobald, Narda, Bonifacino, Aylin C., Lei, Hong, Liu, Taylor Q., Koontz, Sherry, Corsino, Cristina, Zarakas, Marissa A., Desai, Jigar V., Clark, Aaron B., Choi, Uimook, Metzger, Mark E., West, Kamille, Highfill, Steven L., Kang, Elizabeth, Kuhns, Douglas B., Lionakis, Michail S., Stroncek, David F., Dunbar, Cynthia E., Tisdale, John F., Donahue, Robert E., Dahl, Gary A., Malech, Harry L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2020
主題:
Phagocytes, Granulocytes, and Myelopoiesis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724899/
https://ncbi.nlm.nih.gov/pubmed/33284949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003224
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