NADPH oxidase correction by mRNA transfection of apheresis granulocytes in chronic granulomatous disease

Granulocytes from patients with chronic granulomatous disease (CGD) have dysfunctional phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase that fails to generate sufficient antimicrobial reactive oxidative species. CGD patients with severe persistent fungal or bacterial inf...

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Bibliografiset tiedot
Julkaisussa:Blood Adv
Päätekijät: De Ravin, Suk See, Brault, Julie, Meis, Ronald J., Li, Linhong, Theobald, Narda, Bonifacino, Aylin C., Lei, Hong, Liu, Taylor Q., Koontz, Sherry, Corsino, Cristina, Zarakas, Marissa A., Desai, Jigar V., Clark, Aaron B., Choi, Uimook, Metzger, Mark E., West, Kamille, Highfill, Steven L., Kang, Elizabeth, Kuhns, Douglas B., Lionakis, Michail S., Stroncek, David F., Dunbar, Cynthia E., Tisdale, John F., Donahue, Robert E., Dahl, Gary A., Malech, Harry L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2020
Aiheet:
Phagocytes, Granulocytes, and Myelopoiesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724899/
https://ncbi.nlm.nih.gov/pubmed/33284949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003224
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