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Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous disease
In chronic granulomatous disease (CGD), defective phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity causes reduced superoxide anion (O(2)(˙̄)) radical production leading to frequent infections as well as granulomas and impaired wound healing indicative of excessive infl...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947395/ https://ncbi.nlm.nih.gov/pubmed/20511543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233734 |
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