Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous disease

In chronic granulomatous disease (CGD), defective phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity causes reduced superoxide anion (O(2)(˙̄)) radical production leading to frequent infections as well as granulomas and impaired wound healing indicative of excessive infl...

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Bibliografiske detaljer
Main Authors: De Ravin, Suk See, Zarember, Kol A., Long-Priel, Debra, Chan, King C., Fox, Stephen D., Gallin, John I., Kuhns, Douglas B., Malech, Harry L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Phagocytes, Granulocytes, and Myelopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947395/
https://ncbi.nlm.nih.gov/pubmed/20511543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233734
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