Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease

BACKGROUND: Failure to generate phagocyte-derived superoxide and related reactive oxygen intermediates (ROIs) is the major defect in chronic granulomatous disease, causing recurrent infections and granulomatous complications. Chronic granulomatous disease is caused by missense, nonsense, frameshift,...

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Detalhes bibliográficos
Main Authors: Kuhns, Douglas B., Alvord, W. Gregory, Heller, Theo, Feld, Jordan J., Pike, Kristen M., Marciano, Beatriz E., Uzel, Gulbu, DeRavin, Suk See, Long Priel, Debra A., Soule, Benjamin P., Zarember, Kol A., Malech, Harry L., Holland, Steven M., Gallin, John I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069846/
https://ncbi.nlm.nih.gov/pubmed/21190454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1007097
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