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Lessons About the Pathogenesis and Management of Aspergillosis from Studies in Chronic Granulomatous Disease

Chronic Granulomatous Disease (CGD) is a rare disorder caused by mutations in the NADPH oxidase. The CGD phenotype includes granuloma formation and susceptibility to infection with microorganisms including Aspergillus. The immune adjuvant interferon-γ and the antifungal agent itraconazole have reduc...

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Autors principals: Gallin, John I., Zarember, Kol
Format: Artigo
Idioma:Inglês
Publicat: American Clinical and Climatological Association 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863604/
https://ncbi.nlm.nih.gov/pubmed/18528501
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