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Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdh(Q111) Model of HD
Huntington’s disease is a neurodegenerative disorder characterised primarily by motor abnormalities, and is caused by an expanded polyglutamine repeat in the huntingtin protein. Huntingtin dynamically shuttles between subcellular compartments, and the mutant huntingtin protein is mislocalised to cel...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679340/ https://ncbi.nlm.nih.gov/pubmed/26660732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144864 |
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