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A Longitudinal Motor Characterisation of the Hdh(Q111) Mouse Model of Huntington’s Disease

Background: Huntington’s disease (HD) is a rare, incurable neurodegenerative disorder caused by a CAG trinucleotide expansion with the first exon of the huntingtin gene. Numerous knock-in mouse models are currently available for modelling HD. However, before their use in scientific research, these m...

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Vydáno v:J Huntingtons Dis
Hlavní autoři: Yhnell, Emma, Dunnett, Stephen B., Brooks, Simon P.
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942729/
https://ncbi.nlm.nih.gov/pubmed/27258586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-160191
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