Regulation of miR-146a by RelA/NFkB and p53 in STHdh(Q111)/Hdh(Q111) Cells, a Cell Model of Huntington's Disease

Huntington's disease (HD) is caused by the expansion of N-terminal polymorphic poly Q stretch of the protein huntingtin (HTT). Deregulated microRNAs and loss of function of transcription factors recruited to mutant HTT aggregates could cause characteristic transcriptional deregulation associate...

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Detaylı Bibliyografya
Asıl Yazarlar: Ghose, Jayeeta, Sinha, Mithun, Das, Eashita, Jana, Nihar R., Bhattacharyya, Nitai P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162608/
https://ncbi.nlm.nih.gov/pubmed/21887328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023837
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