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Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-A system: insights for transition to Alzheimer Disease
Bach1, among the genes encoded on chromosome 21, is a transcription repressor, which binds to antioxidant response elements (AREs) of DNA thus inhibiting the transcription of specific genes involved in the cell stress response including heme oxygenase-1 (HO-1). HO-1 and its partner, biliverdin reduc...
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| Yayımlandı: | J Alzheimers Dis |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677575/ https://ncbi.nlm.nih.gov/pubmed/25391381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-141254 |
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