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Disturbance of redox homeostasis in Down Syndrome: role of iron dysmetabolism

Down syndrome (DS) is the most common genetic form of intellectual disability that leads in the majority of cases to development of early-onset Alzheimer-like dementia (AD). The neuropathology of DS has several common features with AD including alteration of redox homeostasis, mitochondrial deficits...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Barone, Eugenio, Arena, Andrea, Head, Elizabeth, Butterfield, D Allan, Perluigi, Marzia
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748256/
https://ncbi.nlm.nih.gov/pubmed/28705658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.07.009
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