K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

Estrogens are considered as a major risk factor of endometrial cancer. In this study, we identified a mechanism of tumorigenesis in which K-Ras protein is stabilized via estrogen signaling through the ER-α36 receptor. PKCδ was shown to stabilize K-Ras specifically via estrogen signaling. Estrogens s...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Koo, Kyoung-Hwa, Jeong, Woo-Jeong, Cho, Yong-Hee, Park, Jong-Chan, Min, Do Sik, Choi, Kang-Yell
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673268/
https://ncbi.nlm.nih.gov/pubmed/26015399
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items