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Endometrial Tumorigenesis in Pten(+/−) Mice Is Independent of Coexistence of Estrogen and Estrogen Receptor α

Numerous studies support the role for mutations in the phosphatase and tensin homologue (PTEN) tumor suppressor gene and unopposed estrogen stimulation in the pathogenesis of uterine endometrioid carcinoma. However, the relation between PTEN signaling and estrogen/estrogen receptor in endometrial tu...

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Detalhes bibliográficos
Main Authors: Joshi, Ayesha, Wang, Hong, Jiang, Gaofeng, Douglas, Wayne, Chan, Joanna S.Y., Korach, Kenneth S., Ellenson, Lora H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378854/
https://ncbi.nlm.nih.gov/pubmed/22503752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.03.006
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