The uterine epithelial loss of Pten is inefficient to induce endometrial cancer with intact stromal Pten

Mutation of the tumor suppressor Pten often leads to tumorigenesis in various organs including the uterus. We previously showed that Pten deletion in the mouse uterus using a Pgr-Cre driver (Pten(f/f)Pgr(Cre/+)) results in rapid development of endometrial carcinoma (EMC) with full penetration. We al...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Liang, Xiaohuan, Daikoku, Takiko, Terakawa, Jumpei, Ogawa, Yuya, Joshi, Ayesha R., Ellenson, Lora H., Sun, Xiaofei, Dey, Sudhansu K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126871/
https://ncbi.nlm.nih.gov/pubmed/30142194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007630
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker