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Adenovirus Mediated Homozyogous Endometrial Epithelial Pten Deletion Results in Aggressive Endometrial Carcinoma

PTEN is the most frequently mutated gene in uterine endometriod carcinoma (UEC) and its precursor complex atypical hyperplasia (CAH). Because the mutation frequency is similar in CAH and UEC, PTEN mutations are thought to occur relatively early in endometrial tumorigenesis. Previous work from our la...

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Detalhes bibliográficos
Main Authors: Joshi, Ayesha, Ellenson, Lora Hedrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103602/
https://ncbi.nlm.nih.gov/pubmed/21397598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.03.006
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