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Adenovirus Mediated Homozyogous Endometrial Epithelial Pten Deletion Results in Aggressive Endometrial Carcinoma
PTEN is the most frequently mutated gene in uterine endometriod carcinoma (UEC) and its precursor complex atypical hyperplasia (CAH). Because the mutation frequency is similar in CAH and UEC, PTEN mutations are thought to occur relatively early in endometrial tumorigenesis. Previous work from our la...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103602/ https://ncbi.nlm.nih.gov/pubmed/21397598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.03.006 |
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