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Endometrial Tumorigenesis in Pten(+/−) Mice Is Independent of Coexistence of Estrogen and Estrogen Receptor α

Numerous studies support the role for mutations in the phosphatase and tensin homologue (PTEN) tumor suppressor gene and unopposed estrogen stimulation in the pathogenesis of uterine endometrioid carcinoma. However, the relation between PTEN signaling and estrogen/estrogen receptor in endometrial tu...

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Bibliografske podrobnosti
Main Authors: Joshi, Ayesha, Wang, Hong, Jiang, Gaofeng, Douglas, Wayne, Chan, Joanna S.Y., Korach, Kenneth S., Ellenson, Lora H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378854/
https://ncbi.nlm.nih.gov/pubmed/22503752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.03.006
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