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Endometrial Tumorigenesis in Pten(+/−) Mice Is Independent of Coexistence of Estrogen and Estrogen Receptor α
Numerous studies support the role for mutations in the phosphatase and tensin homologue (PTEN) tumor suppressor gene and unopposed estrogen stimulation in the pathogenesis of uterine endometrioid carcinoma. However, the relation between PTEN signaling and estrogen/estrogen receptor in endometrial tu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Investigative Pathology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378854/ https://ncbi.nlm.nih.gov/pubmed/22503752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.03.006 |
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