Endometrial Tumorigenesis in Pten(+/−) Mice Is Independent of Coexistence of Estrogen and Estrogen Receptor α

Numerous studies support the role for mutations in the phosphatase and tensin homologue (PTEN) tumor suppressor gene and unopposed estrogen stimulation in the pathogenesis of uterine endometrioid carcinoma. However, the relation between PTEN signaling and estrogen/estrogen receptor in endometrial tu...

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Detalles Bibliográficos
Autores principales: Joshi, Ayesha, Wang, Hong, Jiang, Gaofeng, Douglas, Wayne, Chan, Joanna S.Y., Korach, Kenneth S., Ellenson, Lora H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2012
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378854/
https://ncbi.nlm.nih.gov/pubmed/22503752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.03.006
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