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Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells

Cyst enlargement in autosomal dominant polycystic kidney disease (ADPKD) requires the transepithelial secretion of fluid into the cyst lumen. We previously showed that physiological amounts of ouabain enhance cAMP-dependent fluid secretion and cyst growth of human ADPKD cyst epithelial cells in cult...

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Bibliografiske detaljer
Udgivet i:J Membr Biol
Main Authors: Jansson, Kyle, Venugopal, Jessica, Sánchez, Gladis, Magenheimer, Brenda S., Reif, Gail A., Wallace, Darren P., Calvet, James P., Blanco, Gustavo
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672947/
https://ncbi.nlm.nih.gov/pubmed/26289599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-015-9832-7
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