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Overexpression of the polycystin-1 (PC-1) C-tail enhances sensitivity of M-1 cells to ouabain

Cells derived from renal cysts of patients with autosomal dominant polycystic kidney disease (ADPKD) are abnormally sensitive to ouabain, responding to physiological ouabain concentrations with enhanced proliferation and increased forskolin-induced transepithelial fluid secretion. This requires acti...

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Detaylı Bibliyografya
Asıl Yazarlar: Jansson, Kyle, Magenheimer, Brenda S., Maser, Robin L., Calvet, James P., Blanco, Gustavo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051140/
https://ncbi.nlm.nih.gov/pubmed/23784065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-013-9573-4
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