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Adhesion GPCRs as a paradigm for understanding polycystin-1 G protein regulation

Polycystin-1, whose mutation is the most frequent cause of autosomal dominant polycystic kidney disease, is an extremely large and multi-faceted membrane protein whose primary or proximal cyst-preventing function remains undetermined. Accumulating evidence supports the idea that modulation of cellul...

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Опубликовано в: :Cell Signal
Главные авторы: Maser, Robin L., Calvet, James P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485580/
https://ncbi.nlm.nih.gov/pubmed/32305667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109637
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