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Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells

Cyst enlargement in autosomal dominant polycystic kidney disease (ADPKD) requires the transepithelial secretion of fluid into the cyst lumen. We previously showed that physiological amounts of ouabain enhance cAMP-dependent fluid secretion and cyst growth of human ADPKD cyst epithelial cells in cult...

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Detalhes bibliográficos
Publicado no:J Membr Biol
Main Authors: Jansson, Kyle, Venugopal, Jessica, Sánchez, Gladis, Magenheimer, Brenda S., Reif, Gail A., Wallace, Darren P., Calvet, James P., Blanco, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672947/
https://ncbi.nlm.nih.gov/pubmed/26289599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-015-9832-7
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