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Control of Pim2 kinase stability and expression in transformed human haematopoietic cells
The oncogenic Pim2 kinase is overexpressed in several haematological malignancies, such as multiple myeloma and acute myeloid leukaemia (AML), and constitutes a strong therapeutic target candidate. Like other Pim kinases, Pim2 is constitutively active and is believed to be essentially regulated thro...
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| Udgivet i: | Biosci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4672348/ https://ncbi.nlm.nih.gov/pubmed/26500282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150217 |
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