Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is frequently detected in acute myeloid leukemia (AML) patients and is associated with a dismal long-term prognosis. FLT3 tyrosine kinase inhibitors provide short-term disease control, but relapse invariably occurs within months. Pim...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Adv
Hlavní autoři: Green, Alexa S., Maciel, Thiago T., Hospital, Marie-Anne, Yin, Chae, Mazed, Fetta, Townsend, Elizabeth C., Pilorge, Sylvain, Lambert, Mireille, Paubelle, Etienne, Jacquel, Arnaud, Zylbersztejn, Florence, Decroocq, Justine, Poulain, Laury, Sujobert, Pierre, Jacque, Nathalie, Adam, Kevin, So, Jason C. C., Kosmider, Olivier, Auberger, Patrick, Hermine, Olivier, Weinstock, David M., Lacombe, Catherine, Mayeux, Patrick, Vanasse, Gary J., Leung, Anskar Y., Moura, Ivan C., Bouscary, Didier, Tamburini, Jerome
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643770/
https://ncbi.nlm.nih.gov/pubmed/26601252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500221
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky