Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is frequently detected in acute myeloid leukemia (AML) patients and is associated with a dismal long-term prognosis. FLT3 tyrosine kinase inhibitors provide short-term disease control, but relapse invariably occurs within months. Pim...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Green, Alexa S., Maciel, Thiago T., Hospital, Marie-Anne, Yin, Chae, Mazed, Fetta, Townsend, Elizabeth C., Pilorge, Sylvain, Lambert, Mireille, Paubelle, Etienne, Jacquel, Arnaud, Zylbersztejn, Florence, Decroocq, Justine, Poulain, Laury, Sujobert, Pierre, Jacque, Nathalie, Adam, Kevin, So, Jason C. C., Kosmider, Olivier, Auberger, Patrick, Hermine, Olivier, Weinstock, David M., Lacombe, Catherine, Mayeux, Patrick, Vanasse, Gary J., Leung, Anskar Y., Moura, Ivan C., Bouscary, Didier, Tamburini, Jerome
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2015
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643770/
https://ncbi.nlm.nih.gov/pubmed/26601252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500221
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg