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Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia
Cancer cells require nutrients and energy to adapt to increased biosynthetic activity, and protein synthesis inhibition downstream of mammalian target of rapamycin complex 1 (mTORC1) has shown promise as a possible therapy for acute myeloid leukemia (AML). Glutamine contributes to leucine import int...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829119/ https://ncbi.nlm.nih.gov/pubmed/24014241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-493163 |
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