PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model

Brain thiamine homeostasis has an important role in energy metabolism and displays reduced activity in Alzheimer's disease (AD). Thiamine deficiency (TD) induces regionally specific neuronal death in the animal and human brains associated with a mild chronic impairment of oxidative metabolism....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Mouton-Liger, F, Rebillat, A-S, Gourmaud, S, Paquet, C, Leguen, A, Dumurgier, J, Bernadelli, P, Taupin, V, Pradier, L, Rooney, T, Hugon, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669750/
https://ncbi.nlm.nih.gov/pubmed/25590804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.552
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker