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TREM2 regulates microglial cell activation in response to demyelination in vivo

Microglia are phagocytic cells that survey the brain and perform neuroprotective functions in response to tissue damage, but their activating receptors are largely unknown. Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial immunoreceptor whose loss-of-function mutations in hum...

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Détails bibliographiques
Publié dans:Acta Neuropathol
Auteurs principaux: Cantoni, Claudia, Bollman, Bryan, Licastro, Danilo, Xie, Mingqiang, Mikesell, Robert, Schmidt, Robert, Yuede, Carla M., Galimberti, Daniela, Olivecrona, Gunilla, Klein, Robyn S., Cross, Anne H., Otero, Karel, Piccio, Laura
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667728/
https://ncbi.nlm.nih.gov/pubmed/25631124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1388-1
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