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TREM2 regulates microglial cell activation in response to demyelination in vivo
Microglia are phagocytic cells that survey the brain and perform neuroprotective functions in response to tissue damage, but their activating receptors are largely unknown. Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial immunoreceptor whose loss-of-function mutations in hum...
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| Publié dans: | Acta Neuropathol |
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| Auteurs principaux: | , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667728/ https://ncbi.nlm.nih.gov/pubmed/25631124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1388-1 |
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