Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

Triggering receptor expressed on myeloid cells 2 (TREM-2) is a membrane-bound receptor expressed by microglia and macrophages. Engagement of TREM-2 on these cells has been reported to reduce inflammatory responses and, in microglial cells, to promote phagocytosis. TREM-2 function is critical within...

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Detalhes bibliográficos
Main Authors: Piccio, Laura, Buonsanti, Cecilia, Cella, Marina, Tassi, Ilaria, Schmidt, Robert E., Fenoglio, Chiara, Rinker, John, Naismith, Robert T., Panina-Bordignon, Paola, Passini, Nadia, Galimberti, Daniela, Scarpini, Elio, Colonna, Marco, Cross, Anne H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577803/
https://ncbi.nlm.nih.gov/pubmed/18790823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn217
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