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Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status
Low frequency coding variants in TREM2 are associated with increased Alzheimer disease (AD) risk, while loss of functions mutations in the gene lead to an autosomal recessive early-onset dementia, named Nasu-Hakola disease (NHD). TREM2 can be detected as a soluble protein in cerebrospinal fluid (CSF...
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| Publicado no: | Acta Neuropathol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867123/ https://ncbi.nlm.nih.gov/pubmed/26754641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1533-5 |
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