Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) neuropathology is associated with neuroinflammation, but there are few useful biomarkers. Mutant variants of triggering receptor expressed on myeloid cells 2 (TREM2) have recently been linked to late-onset AD and other neurodegenerative disorders. TREM2, a microg...

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Détails bibliographiques
Publié dans:Alzheimers Res Ther
Auteurs principaux: Henjum, Kristi, Almdahl, Ina S., Årskog, Vibeke, Minthon, Lennart, Hansson, Oskar, Fladby, Tormod, Nilsson, Lars N. G.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848774/
https://ncbi.nlm.nih.gov/pubmed/27121148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-016-0182-1
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