Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification

Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies indicate higher CSF sTREM2 in symptomatic AD; however most of these studies...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Knapskog, Anne-Brita, Henjum, Kristi, Idland, Ane-Victoria, Eldholm, Rannveig Sakshaug, Persson, Karin, Saltvedt, Ingvild, Watne, Leiv Otto, Engedal, Knut, Nilsson, Lars N. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522273/
https://ncbi.nlm.nih.gov/pubmed/32985583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72878-8
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