A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease

INTRODUCTION: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 (sTREM2), a proxy of microglial activity, is associated with clinical progre...

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Udgivet i:Alzheimers Dement (Amst)
Main Authors: Edwin, Trine Holt, Henjum, Kristi, Nilsson, Lars N.G., Watne, Leiv Otto, Persson, Karin, Eldholm, Rannveig Sakshaug, Saltvedt, Ingvild, Halaas, Nathalie Bodd, Selbæk, Geir, Engedal, Knut, Strand, Bjørn Heine, Knapskog, Anne‐Brita
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Cerebrospinal Fluid Biomarkers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720866/
https://ncbi.nlm.nih.gov/pubmed/33313376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12128
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