TREM2 regulates microglial cell activation in response to demyelination in vivo

Microglia are phagocytic cells that survey the brain and perform neuroprotective functions in response to tissue damage, but their activating receptors are largely unknown. Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial immunoreceptor whose loss-of-function mutations in hum...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol
Huvudupphovsmän: Cantoni, Claudia, Bollman, Bryan, Licastro, Danilo, Xie, Mingqiang, Mikesell, Robert, Schmidt, Robert, Yuede, Carla M., Galimberti, Daniela, Olivecrona, Gunilla, Klein, Robyn S., Cross, Anne H., Otero, Karel, Piccio, Laura
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667728/
https://ncbi.nlm.nih.gov/pubmed/25631124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1388-1
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