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TREM2 sustains microglial expansion during aging and response to demyelination
Microglia contribute to development, homeostasis, and immunity of the CNS. Like other tissue-resident macrophage populations, microglia express the surface receptor triggering receptor expressed on myeloid cells 2 (TREM2), which binds polyanions, such as dextran sulphate and bacterial LPS, and activ...
Gardado en:
| Publicado en: | J Clin Invest |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463196/ https://ncbi.nlm.nih.gov/pubmed/25893602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77983 |
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