TREM2 triggers microglial density and age‐related neuronal loss

The microglial triggering receptor expressed on myeloid cells 2 (TREM2) signals via the activatory membrane adaptor molecule TYROBP. Genetic variants or mutations of TREM2 or TYROBP have been linked to inflammatory neurodegenerative diseases associated with aging. The typical aging process goes alon...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Linnartz‐Gerlach, Bettina, Bodea, Liviu‐Gabriel, Klaus, Christine, Ginolhac, Aurélien, Halder, Rashi, Sinkkonen, Lasse, Walter, Jochen, Colonna, Marco, Neumann, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590266/
https://ncbi.nlm.nih.gov/pubmed/30548312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23563
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