Microglial CD33-Related Siglec-E Inhibits Neurotoxicity by Preventing the Phagocytosis-Associated Oxidative Burst

Sialic acid-binding Ig-like lectins (Siglecs) are members of the Ig superfamily that recognize sialic acid residues of glycoproteins. Siglec-E is a mouse CD33-related Siglec that preferentially binds to sialic acid residues of the cellular glycocalyx. Here, we demonstrate gene transcription and prot...

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Bibliographische Detailangaben
Hauptverfasser: Claude, Janine, Linnartz-Gerlach, Bettina, Kudin, Alexei P., Kunz, Wolfram S., Neumann, Harald
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2013
Schlagworte:
Brief Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828472/
https://ncbi.nlm.nih.gov/pubmed/24227736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2211-13.2013
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