Neurodegeneration by Activation of the Microglial Complement–Phagosome Pathway

Systemic inflammatory reactions have been postulated to exacerbate neurodegenerative diseases via microglial activation. We now demonstrate in vivo that repeated systemic challenge of mice over four consecutive days with bacterial LPS maintained an elevated microglial inflammatory phenotype and indu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bodea, Liviu-Gabriel, Wang, Yiner, Linnartz-Gerlach, Bettina, Kopatz, Jens, Sinkkonen, Lasse, Musgrove, Ruth, Kaoma, Tony, Muller, Arnaud, Vallar, Laurent, Di Monte, Donato A., Balling, Rudi, Neumann, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608212/
https://ncbi.nlm.nih.gov/pubmed/24948809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5002-13.2014
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