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Neurodegeneration by Activation of the Microglial Complement–Phagosome Pathway

Systemic inflammatory reactions have been postulated to exacerbate neurodegenerative diseases via microglial activation. We now demonstrate in vivo that repeated systemic challenge of mice over four consecutive days with bacterial LPS maintained an elevated microglial inflammatory phenotype and indu...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Bodea, Liviu-Gabriel, Wang, Yiner, Linnartz-Gerlach, Bettina, Kopatz, Jens, Sinkkonen, Lasse, Musgrove, Ruth, Kaoma, Tony, Muller, Arnaud, Vallar, Laurent, Di Monte, Donato A., Balling, Rudi, Neumann, Harald
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608212/
https://ncbi.nlm.nih.gov/pubmed/24948809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5002-13.2014
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