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Sialic Acid on the Neuronal Glycocalyx Prevents Complement C1 Binding and Complement Receptor-3-Mediated Removal by Microglia

Microglial cells are professional phagocytes of the CNS responsible for clearance of unwanted structures. Neuronal processes are marked by complement C1 before they are removed in development or during disease processes. Target molecules involved in C1 binding and mechanisms of clearance are still u...

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Detalhes bibliográficos
Main Authors: Linnartz, Bettina, Kopatz, Jens, Tenner, Andrea J., Neumann, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037907/
https://ncbi.nlm.nih.gov/pubmed/22262892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3830-11.2012
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