Sialic Acid on the Neuronal Glycocalyx Prevents Complement C1 Binding and Complement Receptor-3-Mediated Removal by Microglia

Microglial cells are professional phagocytes of the CNS responsible for clearance of unwanted structures. Neuronal processes are marked by complement C1 before they are removed in development or during disease processes. Target molecules involved in C1 binding and mechanisms of clearance are still u...

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Autors principals: Linnartz, Bettina, Kopatz, Jens, Tenner, Andrea J., Neumann, Harald
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037907/
https://ncbi.nlm.nih.gov/pubmed/22262892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3830-11.2012
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