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Sialic Acid on the Neuronal Glycocalyx Prevents Complement C1 Binding and Complement Receptor-3-Mediated Removal by Microglia

Microglial cells are professional phagocytes of the CNS responsible for clearance of unwanted structures. Neuronal processes are marked by complement C1 before they are removed in development or during disease processes. Target molecules involved in C1 binding and mechanisms of clearance are still u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Linnartz, Bettina, Kopatz, Jens, Tenner, Andrea J., Neumann, Harald
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037907/
https://ncbi.nlm.nih.gov/pubmed/22262892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3830-11.2012
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