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Sialylation of neurites inhibits complement-mediated macrophage removal in a human macrophage-neuron co-culture system

The complement system has been implicated in the removal of dysfunctional synapses and neurites during development and in disease processes in the mouse, but it is unclear how far the mouse data can be transferred to humans. Here, we co-cultured macrophages derived from human THP1 monocytes and neur...

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Publicado en:Glia
Autores principales: Linnartz-Gerlach, Bettina, Schuy, Christine, Shahraz, Anahita, Tenner, Andrea J., Neumann, Harald
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715670/
https://ncbi.nlm.nih.gov/pubmed/26257016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22901
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