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Sialylation of neurites inhibits complement-mediated macrophage removal in a human macrophage-neuron co-culture system

The complement system has been implicated in the removal of dysfunctional synapses and neurites during development and in disease processes in the mouse, but it is unclear how far the mouse data can be transferred to humans. Here, we co-cultured macrophages derived from human THP1 monocytes and neur...

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Publicado en:Glia
Main Authors: Linnartz-Gerlach, Bettina, Schuy, Christine, Shahraz, Anahita, Tenner, Andrea J., Neumann, Harald
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715670/
https://ncbi.nlm.nih.gov/pubmed/26257016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22901
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