載入...
Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies
Direct targeting of RAS, which is frequently mutated, has proven to be challenging, and inhibition of individual downstream RAS mediators has resulted in limited clinical efficacy. We designed a chemical screen to identify compounds capable of potentiating mTOR inhibition in mutant RAS-positive leuk...
Na minha lista:
| 發表在: | Leukemia |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667710/ https://ncbi.nlm.nih.gov/pubmed/24791855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.149 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|